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Article

Differential requirements for STRAD in LKB1-dependent functions in C. elegans.

Development (Cambridge, England) - 1 Feb 2010

Narbonne Patrick, Hyenne Vincent, Li Shaolin, Labbé Jean-Claude, Roy Richard

Abstract excerpt

The protein kinase LKB1 is a crucial regulator of cell growth/proliferation and cell polarity and is the causative gene in the cancer-predisposing disease Peutz-Jeghers syndrome (PJS). The activity of LKB1 is greatly enhanced following its association with the Ste20-like adapter protein STRAD. Un...

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Identifiers

PMID: 20110331
DOI: 10.1242/dev.042044

Genes

GSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20110331-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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