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Article

PPARγ in adipocyte differentiation and metabolism – Novel insights from genome‐wide studies

11 Jun 2010

Abstract excerpt

Adipocyte differentiation is controlled by a tightly regulated transcriptional cascade in which PPARgamma and members of the C/EBP family are key players. Here we review the roles of PPARgamma and C/EBPs in adipocyte differentiation with emphasis on the recently published genome-wide binding profiles for PPARgamma and C/EBPalpha. Interestingly, these analyses show that PPARgamma and C/EBPalpha binding sites are...

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PMID: 20542036
DOI: 10.1016/j.febslet.2010.06.010

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