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Article

Simultaneous CXCL12 and ESR1 CpG island hypermethylation correlates with poor prognosis in sporadic breast cancer.

BMC cancer - 28 Jan 2010

Ramos Edneia A S, Camargo Anamaria A, Braun Karin, Slowik Renata, Cavalli Iglenir J, Ribeiro Enilze M S F, Pedrosa Fábio de O, de Souza Emanuel M, Costa Fabrício F, Klassen Giseli

Abstract excerpt

BACKGROUND: CXCL12 is a chemokine that is constitutively expressed in many organs and tissues. CXCL12 promoter hypermethylation has been detected in primary breast tumours and contributes to their metastatic potential. It has been shown that the oestrogen receptor alpha (ESR1) gene can also be si...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20109227
DOI: 10.1186/1471-2407-10-23
PMCID: PMC2834618

Genes

CXCL12
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20109227-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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