Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA Methylation Status of the Estrogen Receptor α Gene in Canine Mammary Tumors

22 Mar 2018

Abstract excerpt

Estrogen receptor α (ERα) has an important role in mammary carcinogenesis, prognosis, and treatment. In human and canine mammary cancer, the most aggressive tumors show loss of ERα expression, which in human breast cancer has been attributed to methylation of the cytosine followed by guanine (CpG) island within the estrogen receptor α gene ( ESR1) promoter. This study aimed to investigate the role of ESR1 CpG...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29566609
DOI: 10.1177/0300985818763711

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA Methylation Status of the Estrogen Receptor α Gene in Canine Mammary TumorsPMID 29566609Read ↗

Estrogen receptors genotypes and canine mammary neoplasiaSemantic proximity Read ↗

The ESR1 gene is associated with risk for canine mammary tumours.Semantic proximity Read ↗

The distribution pattern of ERα expression, ESR1 genetic variation and expression of growth factor receptors: association with breast cancer prognosis in Russian patients treated with adjuvant tamoxifen.Semantic proximity Read ↗

DNA Methylation Landscape of 16 Canine Somatic Tissues by Methylation-Sensitive Restriction Enzyme-Based Next Generation SequencingSemantic proximity Read ↗

Aberrant DNA methylation suppresses expression of estrogen receptor 1 (ESR1) in ovarian endometriomaSemantic proximity Read ↗

Canine mammary tumors: a review and consensus of standard guidelines on epithelial and myoepithelial phenotype markers, HER2, and hormone receptor assessment using immunohistochemistry.Semantic proximity Read ↗

Promoter mutation and reduced expression of BRCA1 in canine mammary tumors.Semantic proximity Read ↗

Analysis of single nucleotide polymorphisms in the 3' region of the estrogen receptor 1 gene in normal and cryptorchid Miniature Dachshunds and Chihuahuas.Semantic proximity Read ↗

Estrogen receptor alpha gene polymorphisms and breast cancer risk: a case-control study with meta-analysis combined.Semantic proximity Read ↗

Methylation of LINE-1 in cell-free DNA serves as a liquid biopsy biomarker for human breast cancers and dog mammary tumorsSemantic proximity Read ↗

Full-length sequence and expression analysis of estrogen receptor alpha mRNA in feline mammary tumors.Semantic proximity Read ↗

A New Role for ERα: Silencing via DNA Methylation of Basal, Stem Cell, and EMT GenesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.