Article
[Association between sequence variation of Env, Gag genes from the same source and HIV-1 disease progression and host genetic polymorphism].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Jun 2007
Bai Li-shi, Wang Kai-li, Zhou Guang-en, Meng Bin, Liu Yan-cheng, Zeng Yi
Abstract excerpt
OBJECTIVE: To understand the relationship between the HIV-1 viral sequence variation and host factors associated with HIV-1 disease progression. METHODS: Env and gag fragments of HIV-1 were amplified with PCR, cloned and sequenced. Bioinformatics was employed to find the genetic variation, N-linked glycosylation, hypermutation etc. Host gene polymorphism was analysed by using restricted fragment length...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.