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Article

Impact of CD40 gene polymorphisms on the risk of immune thrombocytopenic purpura.

Gene - 30 Apr 2020

AbdelGhafar Muhammad Tarek, El-Kholy Rasha A, Elbedewy Tamer A, Allam Alzahraa A, Eissa Radwa Abd Elmotaleb, Samy Sara Mina, El-Khalik Sara Ragab Abd, Rabah Hanem

Abstract excerpt

OBJECTIVES: To evaluate the relationship between two common single nucleotide polymorphisms (SNPs) of CD40 gene (rs1883832 C/T and rs4810485 G/T) and the risk of immune thrombocytopenia (ITP) in the Egyptian population. METHODS: A case-control study was conducted retrospectively on 101 cases with ITP and 97 healthy subjects. Two SNPs of CD40 gene (rs1883832 C/T and rs4810485 G/T) were genotyped via Taqman allele...

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PMID: 32018016
DOI: 10.1016/j.gene.2020.144419

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