Article
Fluorescent in situ hybridization 1p/19q deletion/imbalance analysis of low-grade and atypical meningiomas.
Neurologia medico-chirurgica - 1 Jan 2010
Nagasaka Toru, Gunji Masaharu, Hosokai Noboru, Hayashi Kumiko, Fujino Masahiko, Ikeda Hiroshi, Ito Masafumi, Inao Suguru
Abstract excerpt
The chromosomal 1p/19q state was analyzed in 16 low-grade meningiomas and 7 atypical meningiomas using fluorescent in situ hybridization (FISH) analysis. Chromosome 1p aberrations were observed in all atypical meningiomas, but in only one low-grade meningioma. Atypical meningiomas showed 19q deletion or imbalance, suggesting chromosomal instability of 19q. A small group of low-grade meningioma showed 19q...
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