Article
Interphase cytogenetics for 1p19q and t(1;19)(q10;p10) may distinguish prognostically relevant subgroups in extraventricular neurocytoma.
Brain pathology (Zurich, Switzerland) - 1 Oct 2009
Rodriguez Fausto J, Mota Renan A, Scheithauer Bernd W, Giannini Caterina, Blair Hilary, New Kent C, Wu Kevin J, Dickson Dennis W, Jenkins Robert B
Abstract excerpt
Co-deletion of chromosome arms 1p and 19q, characteristic of oligodendroglial tumors, was recently found to be mediated by t(1;19)(q10;p10). To evaluate the prevalence of 1p19q co-deletion and t(1;19) in extraventricular neurocytomas (EVN), we studied tumors from 23 patients, including 13 females and 10 males (median age at diagnosis 34 years, range 2-76 years). Fluorescence in situ hybridization (FISH) studies...
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