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Article

Losses of chromosomal arms 1p and 19q in the diagnosis of oligodendroglioma. A study of paraffin-embedded sections.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2001

Burger P C, Minn A Y, Smith J S, Borell T J, Jedlicka A E, Huntley B K, Goldthwaite P T, Jenkins R B, Feuerstein B G

Abstract excerpt

Comparative genomic hybridization (CGH), fluorescence in situ hybridization (FISH), polymerase chain reaction-based microsatellite analysis, and p53 sequencing were performed in paraffin-embedded material from 18 oligodendrogliomas and histologically similar astrocytomas. The study was undertaken because of evidence that concurrent loss of both the 1p and 19q chromosome arms is a specific marker for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11557779
DOI: 10.1038/modpathol.3880400

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