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Article

Cytogenetic analysis of aggressive meningiomas: Possible diagnostic and prognostic implications

15 Jun 1996

Abstract excerpt

BACKGROUND: Published karyotypes from aggressive (atypical and malignant) meningiomas are few, but suggest clonal evolution from benign tumors with monosomy 22 to aggressive forms with additional abnormalities. The goal of this study was to identify the most frequent karyotypic abnormalities associated with aggressive histopathology and biologic behavior. METHODS: Eight intracranial meningiomas exhibiting...

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PMID: 8640707
DOI: 10.1002/(sici)1097-0142(19960615)77:12<2567::aid-cncr21>3.0.co;2-p

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