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Article

A mutation in Mycobacterium tuberculosis rpoB gene confers rifampin resistance in three HIV-TB cases.

Tuberculosis (Edinburgh, Scotland) - 1 Mar 2010

Malhotra Sangita, Cook Victoria J, Wolfe Joyce N, Tang Patrick, Elwood Kevin, Sharma Meenu K

Abstract excerpt

Rifampin is a key component of standard short-course first-line therapy against Mycobacterium tuberculosis (MTB). Rifampin monoresistant MTB, previously a rare phenomenon, is now being reported at increasing rates worldwide. We report a mutation in the rpoB region leading to low level rifampin mo...

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Source

Identifiers

PMID: 20097612
DOI: 10.1016/j.tube.2010.01.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20097612-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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