Article
Direct detection of the hydrolysis of nerve agent model compounds using a fluorescent probe.
Chemico-biological interactions - 6 Sept 2010
Zheng Xueying, Okolotowicz Karl, Wang Beilin, Macdonald Mary, Cashman John R, Zhang Jun
Abstract excerpt
Nerve agents are highly toxic organophosphorus compounds (OPs) that are used as chemical warfare agents. Developing a catalytic bioscavenger to efficiently detoxify nerve agents in the bloodstream of affected individuals has been recognized as an attractive approach to prevent nerve agent toxicity. However, the search for nerve agent catalysts has been hindered by the lack of efficient direct assays for nerve...
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