Oxidized low density lipoprotein-induced transdifferentiation of bone marrow-derived smooth muscle-like cells into foam-like cells in vitro.

doi:10.1111/j.1365-2613.2009.00693.x

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Article

Oxidized low density lipoprotein-induced transdifferentiation of bone marrow-derived smooth muscle-like cells into foam-like cells in vitro.

International journal of experimental pathology - 1 Feb 2010

Yu Jun, Li Yan, Li Mincai, Qu Zhiling, Ruan Qiurong

Abstract excerpt

Oxidized-low density lipoprotein (ox-LDL) is believed to contribute to atherogenesis in part by being taken up into smooth muscle cells (SMC) via specific scavenger receptors; however, it is not clear whether ox-LDL receptor(s) are expressed in bone marrow-derived smooth muscle-like cells (SMLCs) and whether they play a role in the process of SMLC development. Therefore, we examined the ox-LDL-induced...

Topics

Animals
Becaplermin
Biomarkers
Bone Marrow Cells
Cell Separation
Cell Shape
Cell Transdifferentiation
Cells, Cultured
Endocytosis
Flow Cytometry
Foam Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Green Fluorescent Proteins

Lipid Metabolism

Lipoproteins, LDL

Mesenchymal Stem Cells

Mice

Mice, Inbred C57BL

Microfilament Proteins

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Identifiers

PMID: 20096071
DOI: 10.1111/j.1365-2613.2009.00693.x
PMCID: PMC2812725

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