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Article

Olfactomedin 2, a novel regulator for transforming growth factor-β–induced smooth muscle differentiation of human embryonic stem cell–derived mesenchymal cells

9 Oct 2014

Abstract excerpt

Transforming growth factor-β (TGF-β) plays an important role in smooth muscle (SM) differentiation, but the downstream target genes regulating the differentiation process remain largely unknown. In this study, we identified olfactomedin 2 (Olfm2) as a novel regulator mediating SM differentiation. Olfm2 was induced during TGF-β-induced SM differentiation of human embryonic stem cell-derived mesenchymal cells....

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PMID: 25298399
DOI: 10.1091/mbc.e14-08-1255

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