Article
Aldosterone synthase gene (CYP11B2) C-334T polymorphism, ambulatory blood pressure and nocturnal decline in blood pressure in the general Japanese population: the Ohasama Study.
Journal of hypertension - 1 Dec 2001
Matsubara M, Kikuya M, Ohkubo T, Metoki H, Omori F, Fujiwara T, Suzuki M, Michimata M, Hozawa A, Katsuya T, Higaki J, Tsuji I, Araki T, Ogihara T, Satoh H, Hisamichi S, Nagai K, Kitaoka H, Imai Y
Abstract excerpt
OBJECTIVE: The C-344T polymorphism in the 5'-flanking region of the aldosterone synthase (CYP11B2) gene has been suggested to be associated with hypertension and disturbed circadian blood pressure (BP) rhythm through its effect on aldosterone synthesis. However, previous findings on this topic have been inconsistent. DESIGN: A cross-sectional study. SUBJECTS AND METHODS: We investigated the CYP11B2 C-344T...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.