Article
Association of -344C/T polymorphism in the aldosterone synthase (CYP11B2) gene with cardiac and cerebrovascular events in Chinese patients with hypertension.
The Journal of international medical research - 1 Sept 2020
Wang Lili, Zhang Zhi, Liu Dongxia, Yuan Kexin, Zhu Guohua, Qi Xiaoyong
Abstract excerpt
OBJECTIVE: Several recent studies have shown that the aldosterone synthase gene (CYP11B2) -344C/T polymorphism is related to cardiovascular diseases. However, whether the -344C allele influences the incidence of cardiovascular diseases in Chinese patients with hypertension is unclear. METHODS: Chinese patients with essential hypertension were genotyped for the -344C/T polymorphism in CYP11B2 (n = 755; CC,...
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