Article
Lack of mitogen-activated protein kinase phosphatase-1 protects ApoE-null mice against atherosclerosis.
Circulation research - 19 Mar 2010
Shen Jianzhong, Chandrasekharan Unni M, Ashraf Mohammad Z, Long Eric, Morton Richard E, Liu Yusen, Smith Jonathan D, DiCorleto Paul E
Abstract excerpt
RATIONALE: Multiple protein kinases have been implicated in cardiovascular disease; however, little is known about the role of their counterparts: the protein phosphatases. OBJECTIVE: To test the hypothesis that mitogen-activated protein kinase phosphatase (MKP)-1 is actively involved in atheroge...
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