Article
The idic(X)(q13) in myeloid malignancies: breakpoint clustering in segmental duplications and association with TET2 mutations.
Human molecular genetics - 15 Apr 2010
Paulsson Kajsa, Haferlach Claudia, Fonatsch Christa, Hagemeijer Anne, Andersen Mette Klarskov, Slovak Marilyn L, Johansson Bertil
Abstract excerpt
Myelodysplastic syndromes and acute myeloid leukemia with an isodicentric X chromosome [idic(X)(q13)] occur in elderly women and frequently display ringed sideroblasts. Because of the rarity of idic(X)(q13), little is known about its formation, whether a fusion gene is generated, and patterns of additional aberrations. We here present an SNP array study of 14 idic(X)-positive myeloid malignancies, collected...
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