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Article

Heterogeneous breakpoints in patients with acute lymphoblastic leukemia and the dic(9;20)(p11 13;q11) show recurrent involvement of genes at 20q11.21

7 Jul 2009

Abstract excerpt

The dic(9;20)(p11-13;q11) is a recurrent chromosomal abnormality in patients with acute lymphoblastic leukemia. Although it results in loss of material from 9p and 20q, the molecular targets on both chromosomes have not been fully elucidated. From an initial cohort of 58 with acute lymphoblastic leukemia patients with this translocation, breakpoint mapping with fluorescence in situ hybridization on 26 of them...

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Share to Acute Lymphoblastic Leukemia research
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Share to Genomic variations and chromosomal abnormalities

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PMID: 19586940
DOI: 10.3324/haematol.2008.002808

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