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Article

Brain-Derived Neurotrophic Factor (BDNF) as a Predictor of Treatment Response in Schizophrenia and Bipolar Disorder: A Systematic Review.

International journal of molecular sciences - 18 Oct 2024

Liberona Andrés, Jones Natalia, Zúñiga Karen, Garrido Verónica, Zelada Mario Ignacio, Silva Hernán, Nieto Rodrigo R

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is a potential biomarker of response to treatment in psychiatric disorders. As it plays a role in the pathophysiological development of schizophrenia and bipolar disorder, it is of interest to study its role in predicting therapeutic responses in both conditions. We carried out a systematic review of the literature, looking for differences in baseline BDNF levels and the...

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Antipsychotic Agents
Biomarkers
Bipolar Disorder
Brain-Derived Neurotrophic Factor
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Treatment Outcome

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Identifiers

PMID: 39456983
DOI: 10.3390/ijms252011204
PMCID: PMC11508575

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