Article
Role of silent polymorphisms within the dopamine D1 receptor associated with schizophrenia on D1-D2 receptor hetero-dimerization.
Pharmacological reports : PR - 1 Jan 2000
Grymek Katarzyna, Łukasiewicz Sylwia, Faron-Góreckaa Agata, Tworzydlo Magdalena, Polit Agnieszka, Dziedzicka-Wasylewska Marta
Abstract excerpt
Within the coding region of the dopamine D(1) receptor (D(1)R), two synonymous polymorphisms, D(1)R(G198A) and D(1)R(G1263), have been identified and postulated to correlate with the schizophrenia phenotype. Binding studies revealed that the density of these genetic variants was much lower than t...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
