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Article

Processes and patterns: Insights on cranial covariation from an Apert syndrome mouse model.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 2022

Singh Nandini, Heuzé Yann, Holmes Greg

Abstract excerpt

BACKGROUND: Major cell-to-cell signaling pathways, such as the fibroblast growth factors and their four receptors (FGF/FGFR), are conserved across a variety of animal forms. FGF/FGFRs are necessary to produce several "vertebrate-specific" structures, including the vertebrate head. Here, we examine the effects of the FGFR2 S252W mutation associated with Apert syndrome on patterns of cranial integration. Our data...

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PMID: 35582939
DOI: 10.1002/dvdy.498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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