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Article

Investigating the impact of the Down syndrome related common MTHFR 677C>T polymorphism in the Danish population.

Disease markers - 1 Jan 2009

Kokotas Haris, Grigoriadou Maria, Mikkelsen Margareta, Giannoulia-Karantana Aglaia, Petersen Michael B

Abstract excerpt

Chromosomal aneuploidy consists the leading cause of fetal death in our species. Around 50% of spontaneous abortions until 15 weeks of gestational age are chromosomally aneuploid, with trisomies accounting for 50% of the abnormal abortions. Trisomy 21 is the most common chromosome abnormality in liveborns and is usually the result of nondisjunction of chromosome 21 in meiosis in either oogenesis or...

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Source

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Identifiers

PMID: 20075510
DOI: 10.3233/DMA-2009-0673
PMCID: PMC3835277

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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