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Meta-analysis of Methylenetetrahydrofolate reductase maternal gene in Down syndrome: increased susceptibility in women carriers of the MTHFR 677T allele.

Molecular biology reports - 1 Aug 2014

Victorino D B, Godoy M F, Goloni-Bertollo E M, Pavarino E C

Abstract excerpt

Because a number of data studies include some controversial results about Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and Down syndrome (DS), we performed a meta-analysis to determine a more precise estimation of this association. Studies were searched on PubMed, EMBASE and Lilacs-Scielo, up to April 2013, and they were eligible if they included case mothers (DSM) that have gave birth to children...

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Identifiers

PMID: 24913031
DOI: 10.1007/s11033-014-3424-y

Genes

MTHFR

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Meta-analysis of Methylenetetrahydrofolate reductase maternal gene in Down syndrome: increased susceptibility in women carriers of the MTHFR 677T allele.PMID 24913031Read ↗

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