Article
MicroRNA profiling predicts a variance in the proliferative potential of cardiac progenitor cells derived from neonatal and adult murine hearts.
Journal of molecular and cellular cardiology - 1 Jan 2012
Sirish Padmini, López Javier E, Li Ning, Wong Andrew, Timofeyev Valeriy, Young J Nilas, Majdi Maryam, Li Ronald A, Chen Huei-Sheng Vincent, Chiamvimonvat Nipavan
Abstract excerpt
Cardiac progenitor cells (CPCs) are multipotent cells that may offer tremendous potentials for the regeneration of injured myocardium. To expand the limited number of CPCs for effective clinical regeneration of myocardium, it is important to understand their proliferative potentials. Single-cell based assays were utilized to purify c-kit(pos) CPCs from human and mouse hearts. MicroRNA profiling identified eight...
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