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Article

Evolutionary Dynamics of Complex Networks of HIV Drug-Resistant Strains: The Case of San Francisco

5 Feb 2010

Abstract excerpt

Over the past two decades, HIV resistance to antiretroviral drugs (ARVs) has risen to high levels in the wealthier countries of the world, which are able to afford widespread treatment. We have gained insights into the evolution and transmission dynamics of ARV resistance by designing a biologically complex multistrain network model. With this model, we traced the evolutionary history of ARV resistance in San...

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PMID: 20075214
DOI: 10.1126/science.1180556

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