Article

Biosynthesis of the redox cofactor mycofactocin comprises oligoglycosylation by MftF in <i>Mycolicibacterium smegmatis</i>

2019-10-29

Abstract excerpt

Mycofactocin (MFT) is a redox cofactor involved in alcohol metabolism of mycobacteria including Mycobacterium tuberculosis . In recent years, a preliminary biosynthetic model of MFT has been established by in-vitro studies, while the final structure of MFT remained elusive. Here, we report the discovery of MFT by metabolomics and establish a model of its biosynthesis in Mycolicibacterium smegmatis . Structure e...

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Literature Corpus work: 266f5f8c-6925-5556-8cff-fc006355da2d
DOI: 10.1101/821413

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