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Article

Endogenous rhythms in Period1 mutant suprachiasmatic nuclei in vitro do not represent circadian behavior.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 18 Nov 2009

Pendergast Julie S, Friday Rio C, Yamazaki Shin

Abstract excerpt

The mammalian circadian pacemaker in the suprachiasmatic nuclei (SCN) controls daily rhythms of behavior and physiology. Lesions of the SCN cause arrhythmicity of locomotor activity, and transplants of fetal SCN tissue restore rhythmic behavior that is consistent with the periodicity of the donor's genotype, suggesting that the SCN determines the period of the circadian behavioral rhythm. While several studies...

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Identifiers

PMID: 19923301
DOI: 10.1523/JNEUROSCI.3261-09.2009
PMCID: PMC2806308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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