GRM7 variants confer susceptibility to age-related hearing impairment.

doi:10.1093/hmg/ddn402

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Article

GRM7 variants confer susceptibility to age-related hearing impairment.

Human molecular genetics - 15 Feb 2009

Friedman Rick A, Van Laer Lut, Huentelman Matthew J, Sheth Sonal S, Van Eyken Els, Corneveaux Jason J, Tembe Waibhav D, Halperin Rebecca F, Thorburn Ashley Q, Thys Sofie, Bonneux Sarah, Fransen Erik, Huyghe Jeroen, Pyykkö Ilmari, Cremers Cor W R J, Kremer Hannie, Dhooge Ingeborg, Stephens Dafydd, Orzan Eva, Pfister Markus, Bille Michael, Parving Agnete, Sorri Martti, Van de Heyning Paul H, Makmura Linna, Ohmen Jeffrey D, Linthicum Frederick H, Fayad Jose N, Pearson John V, Craig David W, Stephan Dietrich A, Van Camp Guy

Abstract excerpt

Age-related hearing impairment (ARHI), or presbycusis, is the most prevalent sensory impairment in the elderly. ARHI is a complex disease caused by an interaction between environmental and genetic factors. Here we describe the results of the first whole genome association study for ARHI. The study was performed using 846 cases and 846 controls selected from 3434 individuals collected by eight centers in six...

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Identifiers

PMID: 19047183
DOI: 10.1093/hmg/ddn402
PMCID: PMC2638831

Genes

GRM7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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