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Article

Comparison of clastogen-induced gene expression profiles in wild-type and DNA repair-deficient Rad54/Rad54B cells.

BMC genomics - 12 Jan 2010

Mahabir Anuska G, Schaap Mirjam M, Pennings Jeroen L A, van Benthem Jan, Hendriksen Coenraad F M, van Steeg Harry

Abstract excerpt

BACKGROUND: Previously we found that Rad54/Rad54B cells are more sensitive towards mitomycin C (MMC) as compared to wild-type (WT) cells. This difference in sensitivity was absent upon exposure to other clastogens like bleomycin (BLM) and gamma-radiation. In order to get further insight into possible underlying mechanisms, gene expression changes in WT and Rad54/Rad54B MEFs (mouse embryonic fibroblasts) after...

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Source

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Identifiers

PMID: 20067618
DOI: 10.1186/1471-2164-11-24
PMCID: PMC2824718

Genes

BLM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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