Polymorphisms of the HTR2C gene and antipsychotic-induced weight gain: an update and meta-analysis.

doi:10.2217/pgs.10.123

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Article

Polymorphisms of the HTR2C gene and antipsychotic-induced weight gain: an update and meta-analysis.

Pharmacogenomics - 1 Nov 2010

Sicard Michelle N, Zai Clement C, Tiwari Arun K, Souza Renan P, Meltzer Herbert Y, Lieberman Jeffrey A, Kennedy James L, Müller Daniel J

Abstract excerpt

AIMS: This study aims to test for possible associations between the gene coding for the 5-HT2C receptor and antipsychotic-induced weight gain. MATERIALS & METHODS: Four HTR2C polymorphisms (rs498207, C-759T, G-697C and Ser23Cys) were investigated in our sample of 205 chronic schizophrenia patients. RESULTS: Significant over-representation of the C-G-Cys23 haplotype in patients with weight gain (OR: 1.93; 95% CI:...

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PMID: 21121776
DOI: 10.2217/pgs.10.123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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