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-759C>T Polymorphism of the HTR2C Gene is Associated with Second Generation Antipsychotic-Induced Weight Gain in Female Patients with Schizophrenia.

Pharmacopsychiatry - 1 Jan 2017

Daray Federico Manuel, Rodante Demián, Carosella Laura G, Silva María Elena, Martínez Melina, Fernández Busch María V, Faccone Diego F, Rothlin Rodolfo P, Maffía Paulo C

Abstract excerpt

Introduction: The HTR2C gene is an important candidate in pharmacogenetic studies of antipsychotic-induced weight gain (AIWG). However, inconsistent results have been obtained. The present study investigated the association between -759C>T, functional polymorphism of the HTR2C receptor, and AIWG. Methods: A prospective cohort of 48 female inpatients with schizophrenia and related illness treated according to...

Topics

Adult
Antipsychotic Agents
Female
Genetic Testing
Humans
Logistic Models
Middle Aged
Polymorphism, Single Nucleotide
Psychiatric Status Rating Scales
Receptor, Serotonin, 5-HT2C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Schizophrenia

Weight Gain

Young Adult

Source

Identifiers

PMID: 27414739
DOI: 10.1055/s-0042-110321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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