Article
Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells.
The Journal of biological chemistry - 19 Mar 2010
Lu Tung-Ying, Lu Ruei-Min, Liao Mei-Ying, Yu John, Chung Chu-Hung, Kao Cheng-Fu, Wu Han-Chung
Abstract excerpt
Human embryonic stem cells (hESCs) are unique pluripotent cells capable of self-renewal and differentiation into all three germ layers. To date, more cell surface markers capable of reliably identifying hESCs are needed. The epithelial cell adhesion molecule (EpCAM) is a type I transmembrane glycoprotein expressed in several progenitor cell populations and cancers. It has been used to enrich cells with...
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