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Article

In vivo fluorescent detection of Fe-S clusters coordinated by human GRX2.

Chemistry & biology - 24 Dec 2009

Hoff Kevin G, Culler Stephanie J, Nguyen Peter Q, McGuire Ryan M, Silberg Jonathan J, Smolke Christina D

Abstract excerpt

A major challenge to studying Fe-S cluster biosynthesis in higher eukaryotes is the lack of simple tools for imaging metallocluster binding to proteins. We describe the first fluorescent approach for in vivo detection of 2Fe2S clusters that is based upon the complementation of Venus fluorescent p...

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Source

Identifiers

PMID: 20064440
DOI: 10.1016/j.chembiol.2009.11.011

Genes

ISCU
NFS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20064440-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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