Article

Combinatorial in silico approach for cancer-associated [4Fe-4S] metalloprotein discovery

2024-08-23

Abstract excerpt

Iron-sulfur (Fe-S) metalloproteins play vital roles in cellular processes, including DNA replication and repair. Though Fe-S protein dysregulation has been suggested to be associated with developmental and cancerous diseases, only a few Fe-S proteins with genome maintenance roles have been identified experimentally, likely because Fe-S cluster is susceptible to degradation under oxic environment. In vitro, Fe-S cl...

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Literature Corpus work: ccf5d4c2-bd2d-55a2-aa1b-8ea1e3768666
DOI: 10.22541/au.172445614.46971169/v1

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