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Article

alpha-synuclein and LRRK2: partners in crime.

Neuron - 24 Dec 2009

Tong Youren, Shen Jie

Abstract excerpt

In this issue of Neuron, Lin et al. report that LRRK2 modulates age-related neurodegeneration caused by overexpression of alpha-synuclein in the forebrain of transgenic mice. Overexpression of LRRK2 accelerates the progression of alpha-synuclein-mediated neuropathological changes, whereas deletio...

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Identifiers

PMID: 20064381
DOI: 10.1016/j.neuron.2009.12.017
PMCID: PMC2826885

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20064381-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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