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Article

KIT mutations confer a distinct gene expression signature in core binding factor leukaemia.

British journal of haematology - 1 Mar 2010

Lück Sonja C, Russ Annika C, Du Juan, Gaidzik Verena, Schlenk Richard F, Pollack Jonathan R, Döhner Konstanze, Döhner Hartmut, Bullinger Lars

Abstract excerpt

Core binding factor (CBF) leukaemias, characterized by either inv(16)(p13.1q22) or t(8;21)(q22;q22), constitute acute myeloid leukaemia (AML) subgroups with favourable prognosis. However, 40-50% of patients relapse, emphasizing the need for risk-adapted treatment approaches. In this regard, study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Leukemia, Myeloid, Acute

Share to Neoplasm Proteins

Share to Oligonucleotide Array Sequence Analysis

Share to Proto-Oncogene Proteins c-kit

Source

Identifiers

PMID: 20064158
DOI: 10.1111/j.1365-2141.2009.08035.x

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20064158-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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KIT mutations confer a distinct gene expression signature in core binding factor leukaemia.PMID 20064158Read ↗

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