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Article

KIT Mutant/Core binding factor-negative acute myeloid leukemia might be a complex subgroup with dismal prognosis: a single-center retrospective analysis.

Annals of hematology - 20 Jan 2026

Jiang Rui, Zhang Zhibo, Liu Yizi, Qu Wenqiang, Zeng Zhao, Wang Linlin, Wang Qian, Yin Jia, Chen Suning

Abstract excerpt

KIT mutations are well-established as poor prognostic markers in core binding factor AML (CBF AML). However, data on KIT mutation in CBF-negative (CBF-neg) AML remains scarce. This retrospective study aimed to characterize the clinical features and outcomes of patients with KIT mutant (KIT mut)/CBF-neg AML. We conducted a retrospective study in our single center and identified non-M3 de novo AML with KIT...

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Identifiers

PMID: 41557053
DOI: 10.1007/s00277-026-06814-7
PMCID: PMC12819538

Genes

KIT
EFS
NRAS
WT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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KIT Mutant/Core binding factor-negative acute myeloid leukemia might be a complex subgroup with dismal prognosis: a single-center retrospective analysis.PMID 41557053Read ↗

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