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Article

A synonymous variant in scavenger receptor, class B, type I gene is associated with lower SR-BI protein expression and function.

Atherosclerosis - 1 May 2010

Constantineau Jason, Greason Erin, West Michael, Filbin Megan, Kieft Jeffrey S, Carletti Martha Z, Christenson Lane K, Rodriguez Annabelle

Abstract excerpt

OBJECTIVE: A synonymous variant within scavenger receptor class B type I gene (SCARB1), exon 8 rs5888, has been associated with altered lipid levels and cardiovascular risk in humans. The objective was to determine if rs5888 decreased SR-BI protein expression and function in vitro. METHODS: SR-BI RNA secondary structure, turnover, polysomal distribution and protein expression were examined in COS cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 20060115
DOI: 10.1016/j.atherosclerosis.2009.11.029
PMCID: PMC3342769

Genes

SCARB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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