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Article

Impact of genetic variants in human scavenger receptor class B type I (SCARB1) on plasma lipid traits.

Circulation. Cardiovascular genetics - 1 Dec 2014

Niemsiri Vipavee, Wang Xingbin, Pirim Dilek, Radwan Zaheda H, Hokanson John E, Hamman Richard F, Barmada M Michael, Demirci F Yesim, Kamboh M Ilyas

Abstract excerpt

BACKGROUND: Scavenger receptor class B type 1 (SCARB1) plays an important role in high-density lipoprotein cholesterol (HDL-C) metabolism in selective cholesteryl ester uptake and in free cholesterol cellular efflux. METHODS AND RESULTS: This study aims to identify common (minor allele frequency ≥5%) and low-frequency/rare (minor allele frequency <5%) variants, using resequencing all 13 exons and exon-intron...

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Topics

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Share to Apolipoproteins B
Share to Cholesterol, HDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Association Studies

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Scavenger Receptors, Class B

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 25245032
DOI: 10.1161/CIRCGENETICS.114.000559
PMCID: PMC4270916

Genes

SCARB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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