Article
Identification of novel SNPs in SYK gene of breast cancer patients: computational analysis of SNPs in the 5'UTR.
Molecular biology reports - 1 Aug 2012
Kanwal Sehrish, Kayani Mahmood Akhtar, Faryal Rani
Abstract excerpt
Spleen tyrosine kinase (SYK) is a non receptor type tyrosine kinase and a known candidate tumor suppressor gene in breast carcinoma. Loss of Syk is associated with breast cancer invasion and increased cell mortality. The main goal of our study was to detect germ-line polymorphisms in SYK gene in...
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