Article
Risk-reducing mastectomy and salpingo-oophorectomy in unaffected BRCA mutation carriers: uptake and timing.
Clinical genetics - 1 Apr 2010
Skytte A-B, Gerdes A-M, Andersen M K, Sunde L, Brøndum-Nielsen K, Waldstrøm M, Kølvraa S, Crüger D
Abstract excerpt
Once female carriers of a BRCA mutation are identified they have to make decisions on risk management. The aim of this study is to outline the uptake of risk-reducing surgery in the Danish population of BRCA mutation positive women and to search for factors affecting this decision. We analysed data from 306 healthy BRCA carriers with no personal history of ovarian or breast cancer. We found a 10-year uptake of...
Topics
- Adult
- Aged
- BRCA1 Protein
- BRCA2 Protein
- Fallopian Tubes
- Female
- Heterozygote
- Humans
- Mastectomy
- Middle Aged
- Mutation
- Ovariectomy