The effect of personal medical history and family history of cancer on the uptake of risk-reducing salpingo-oophorectomy.

doi:10.1007/s10689-015-9827-7

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Article

The effect of personal medical history and family history of cancer on the uptake of risk-reducing salpingo-oophorectomy.

Familial cancer - 1 Dec 2015

van der Aa Jessica E, Hoogendam Jacob P, Butter Els S F, Ausems Margreet G E M, Verheijen René H M, Zweemer Ronald P

Abstract excerpt

Women with an increased lifetime risk of ovarian cancer are advised to undergo risk-reducing salpingo-oophorectomy (RRSO) to reduce risk of adnexal cancer. We investigated the uptake of RRSO and evaluated the influence of personal medical history of (breast) cancer, risk-reducing mastectomy (RRM) and family history of ovarian and/or breast cancer on the RRSO decision. This single center retrospective...

Topics

Adult
Aged
BRCA1 Protein
BRCA2 Protein
Female
Follow-Up Studies
Genetic Predisposition to Disease
Germ-Line Mutation
Heterozygote
Humans
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Staging

Netherlands

Ovarian Neoplasms

Ovariectomy

Patient Acceptance of Health Care

Prognosis

Retrospective Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 26264902
DOI: 10.1007/s10689-015-9827-7
PMCID: PMC4630248

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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