Article
Uptake, time course, and predictors of risk-reducing surgeries in BRCA carriers.
Genetic testing and molecular biomarkers - 1 Feb 2009
Beattie Mary S, Crawford Beth, Lin Feng, Vittinghoff Eric, Ziegler John
Abstract excerpt
INTRODUCTION AND AIMS: For women who carry BRCA mutations, risk-reducing surgeries are an option to decrease breast and ovarian cancer risk. This study aims to determine the uptake, time course, and predictors of risk-reducing mastectomy (RRM) and risk-reducing salpingo-oophorectomy (RRSO) in BRCA carriers. RESULTS: In 272 female carriers, followed for a median of 3.7 years, 23% of those eligible chose RRM, and...
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