Article
Uptake of risk-reducing salpingo-oophorectomy in women carrying a BRCA1 or BRCA2 mutation: evidence for lower uptake in women affected by breast cancer and older women.
British journal of cancer - 14 Feb 2012
Sidon L, Ingham S, Clancy T, Clayton R, Clarke A, Jones E A, Lalloo F, Evans D G R
Abstract excerpt
BACKGROUND: Bilateral risk-reducing salpingo-oophorectomy (BRRSO) is the only effective way of reducing mortality from ovarian cancer. This study investigates uptake of BRRSO in 700 BRCA1/2 mutation carriers from Greater Manchester. METHODS: Dates of last follow-up and BRRSO were obtained, and the following variables were investigated: ovarian cancer risk/gene, age and breast cancer history. The date of the...
Topics
- Adult
- Aged
- Aged, 80 and over
- Breast Neoplasms
- Female
- Genes, BRCA1
- Genes, BRCA2
- Genetic Predisposition to Disease
- Humans
- Middle Aged
- Mutation
- Ovarian Neoplasms
- Ovariectomy
- Risk Factors