Article
Activation functions of transcription factor Sp1 at U2 snRNA and TATA box promoters.
Biological chemistry Hoppe-Seyler - 1 Nov 1995
Forsberg M, Ström A C, Lillhager P, Westin G
Abstract excerpt
To localize regions in the human transcription factor Sp1, which are involved in activating transcription of the U2 snRNA gene promoter and of a TATA box gene promoter, the activation potentials of GAL4/Sp1 chimeras were analyzed in mammalian cells. In vitro mutagenesis analysis of Sp1 showed tha...
Topics
- Base Sequence
- Biotransformation
- Cells, Cultured
- DNA
- Electrophoresis, Polyacrylamide Gel
- Humans
- Molecular Sequence Data
- Mutation
- Plasmids
- Promoter Regions, Genetic
- RNA, Small Nuclear
- Sp1 Transcription Factor
