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Article

Dexamethasone treatment during the expansion phase maintains stemness of bone marrow mesenchymal stem cells.

Journal of tissue engineering and regenerative medicine - 1 Jul 2010

Xiao Yanling, Peperzak Victor, van Rijn Linda, Borst Jannie, de Bruijn Joost D

Abstract excerpt

Human mesenchymal stem cells (hMSCs) can form various mesodermal tissues when grown under appropriate conditions. Dexamethasone (Dex) is regularly used to stimulate the osteogenic potential of hMSCs and it has recently been reported to increase the cell expansion rate. In this study we have investigated the effect of low-dose Dex treatment (10(-8) M) on the multipotency of expanded hMSCs, using histological,...

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Identifiers

PMID: 20058244
DOI: 10.1002/term.250

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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