Osteoblast differentiation of human bone marrow cells under continuous and discontinuous treatment with dexamethasone.

doi:10.1590/s0103-64402005000200013

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Article

Osteoblast differentiation of human bone marrow cells under continuous and discontinuous treatment with dexamethasone.

Brazilian dental journal - 1 Jan 2005

Beloti Márcio Mateus, Rosa Adalberto Luiz

Abstract excerpt

Dexamethasone (Dex) has been shown to induce osteoblast differentiation in several cell culture systems. This study investigated the effect of continuous and discontinuous treatment with Dex on osteoblast differentiation of human bone marrow stromal cells (BMSC). Primary culture and first passage were cultured in media with or without Dex 10(-7) M. During the culture period, cells were incubated at 37 degrees C...

Topics

Alkaline Phosphatase
Anti-Inflammatory Agents
Bone Marrow Cells
Cell Count
Cell Differentiation
Cell Proliferation
Cell Survival
Cells, Cultured
Dexamethasone
Glucocorticoids
Humans
Osteoblasts
Osteogenesis
Phenotype
Proteins
Stromal Cells

Source

Open in PubMed

Identifiers

PMID: 16475612
DOI: 10.1590/s0103-64402005000200013

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