Article
Comparative cellular and molecular analyses of pooled bone marrow multipotent mesenchymal stromal cells during continuous passaging and after successive cryopreservation.
Journal of cellular biochemistry - 1 Oct 2012
Mamidi Murali Krishna, Nathan Kavitha Ganesan, Singh Gurbind, Thrichelvam Saratha Thevi, Mohd Yusof Nurul Ain Nasim, Fakharuzi Noor Atiqah, Zakaria Zubaidah, Bhonde Ramesh, Das Anjan Kumar, Majumdar Anish Sen
Abstract excerpt
The clinical application of human bone marrow derived multipotent mesenchymal stromal cells (MSC) requires expansion, cryopreservation, and transportation from the laboratory to the site of cell implantation. The cryopreservation and thawing process of MSCs may have important effects on the viability, growth characteristics and functionality of these cells both in vitro and in vivo. More importantly, MSCs after...
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