Article
Importance of Sox2 in maintenance of cell proliferation and multipotency of mesenchymal stem cells in low-density culture.
Cell proliferation - 1 Oct 2011
Yoon D S, Kim Y H, Jung H S, Paik S, Lee J W
Abstract excerpt
OBJECTIVES: This study has aimed to repopulate 'primitive' cells from late-passage mesenchymal stem cells (MSCs) of poor multipotentiality and low cell proliferation rate, by simply altering plating density. MATERIALS AND METHODS: Effects of low density culture compared t high density culture on late-passage bone marrow (BM)-derived MSCs and pluripotency markers of multipotentiality were investigated. Cell...
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